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  • Synthesis of new 1,3,4-benzotriazepin-5-one

    New derivatives of 1,3,4-benzotriazepin-5-one were designed and synthesized as structural analogues to the antitumor agents devazepide and asperlicin. An efficient and novel approach to the synthesis of 2-amino-1,3,4-benzotriazepin-5-one 2 was developed and its structure was confirmed. The newly synthesized derivatives were evaluated for their in vitro antitumor activity on 60 different cell ...

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  • Antifungals | SCBT - Santa Cruz Biotechnology

    100 mg 1 g 5 g: 28.00 56.00 151.00 86 (4) Staurosporine Staurosporine is an antifungal inhibitor ... 5-Fluoro isatin 5-Fluoro isatin is a reactant for the preparation of many compounds ... CAS: 5448-47-5, MF: C 10 H 11 N 3 O, MW: 189.21

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  • Discovery of a Quinoline-4-carboxamide Derivative

    2019-5-26 · The antiplasmodial activity, DMPK properties, and efficacy of a series of quinoline-4-carboxamides are described. This series was identified from a phenotypic screen against the blood stage of Plasmodium falciparum (3D7) and displayed moderate potency but with suboptimal physicochemical properties and poor microsomal stability. The screening hit (1, EC50 = 120 nM) was optimized to lead ...

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  • Synthesis of a new series of 3-functionalised-1-phenyl

    Synthesis of 3-(chlorosulfonyl)benzoic acid derivatives (2a–d) To the stirred chlorosulfonic acid (13.6 ml, 204.5 mmol) at 0 °C, 4-Substituted benzoic acid derivatives (1a–d) (5 g, 40.9 mmol) were added portion wise and then stirred at 110 °C for 5 to 8 h.

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  • OOPS - Chemical Reviews

    Wed, 27 Jan 2021. Biochemistry provides an international forum for publishing exceptional, rigorous, high-impact research across all of biological chemistry. This broad scope includes studies on the chemical, physical, mechanistic, and/or structural basis of biological or cell function.

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  • Organic Compounds | Διερευνητική Μάθηση

    This website uses cookies to improve your experience while you navigate through the website. Out of these cookies, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website.

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  • Photochemical benzylic bromination in continuous

    Photochemical benzylic bromination (the Wohl–Ziegler reaction) represents one of the most well used methods within synthetic organic photochemistry. 1,2 This simple procedure is initiated by the photolysis of the Br–Br bond in Br 2, present in low levels in the synthetic reagent N-bromosuccinimide (NBS). 3–6 However, despite the simplicity and wide implementation of this methodology, it ...

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  • Lab Chemicals supplier in Dubai, Sharjah, Fujairah UAE ...

    2 天前 · CAS No HSN Product 159000 13012000 Acacia Gum Acaacia 55589-62-3 29349900 AceSulfame Potassium 75-07-0 29121200 Acetaldehyde Solution 20-30% 60-35-5 29241900 Acetamide 98% 103-84-4 29242910 Acetanilide (N-Phenylacetamide)98.5% 102-01-2 29242920 Acetoacetanilide Purified 98% 616-91-1 29309040 N-Acetyl -L- Cysteine 99% 50-78-2 29182310 Acetylsalicylic acid …

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  • (PDF) Sulphonamides incorporating 1,3,5-triazine ...

    2011-9-19 · 化工原料和产品中英文对照 .doc

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  • Synthesis of new 1,3,4-benzotriazepin-5-one

    New derivatives of 1,3,4-benzotriazepin-5-one were designed and synthesized as structural analogues to the antitumor agents devazepide and asperlicin. An efficient and novel approach to the synthesis of 2-amino-1,3,4-benzotriazepin-5-one 2 was developed and its structure was confirmed. The newly synthesized derivatives were evaluated for their in vitro antitumor activity …

    Get Price
  • Antifungals | SCBT - Santa Cruz Biotechnology

    100 mg 1 g 5 g: 28.00 56.00 151.00 86 (4) Staurosporine Staurosporine is an antifungal inhibitor ... 5-Fluoro isatin 5-Fluoro isatin is a reactant for the preparation of many compounds ... CAS: 5448-47-5, MF: C 10 H 11 N 3 O, MW: 189.21

    Get Price
  • Discovery of a Quinoline-4-carboxamide Derivative

    2019-5-26 · The antiplasmodial activity, DMPK properties, and efficacy of a series of quinoline-4-carboxamides are described. This series was identified from a phenotypic screen against the blood stage of Plasmodium falciparum (3D7) and displayed moderate potency but with suboptimal physicochemical properties and poor microsomal stability. The screening hit (1, EC50 = 120 …

    Get Price
  • Synthesis of a new series of 3-functionalised-1

    Synthesis of 3-(chlorosulfonyl)benzoic acid derivatives (2a–d) To the stirred chlorosulfonic acid (13.6 ml, 204.5 mmol) at 0 °C, 4-Substituted benzoic acid derivatives (1a–d) (5 g, 40.9 mmol) were added portion wise and then stirred at 110 °C for 5 to 8 h.

    Get Price
  • OOPS - Chemical Reviews

    Wed, 27 Jan 2021. Biochemistry provides an international forum for publishing exceptional, rigorous, high-impact research across all of biological chemistry. This broad scope includes studies on the chemical, physical, mechanistic, and/or structural basis of biological or cell function.

    Get Price
  • Organic Compounds | Διερευνητική Μάθηση

    This website uses cookies to improve your experience while you navigate through the website. Out of these cookies, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website.

    Get Price
  • Photochemical benzylic bromination in continuous

    Photochemical benzylic bromination (the Wohl–Ziegler reaction) represents one of the most well used methods within synthetic organic photochemistry. 1,2 This simple procedure is initiated by the photolysis of the Br–Br bond in Br 2, present in low levels in the synthetic reagent N-bromosuccinimide (NBS). 3–6 However, despite the simplicity and wide implementation of this …

    Get Price
  • Lab Chemicals supplier in Dubai, Sharjah, Fujairah

    2 天前 · CAS No HSN Product 159000 13012000 Acacia Gum Acaacia 55589-62-3 29349900 AceSulfame Potassium 75-07-0 29121200 Acetaldehyde Solution 20-30% 60-35-5 29241900 Acetamide 98% 103-84-4 29242910 Acetanilide (N-Phenylacetamide)98.5% 102-01-2 29242920 Acetoacetanilide Purified 98% 616-91-1 29309040 N-Acetyl -L- Cysteine 99% 50-78-2 …

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  • (PDF) Sulphonamides incorporating 1,3,5-triazine ...

    2011-9-19 · 化工原料和产品中英文对照 .doc

    Get Price
  • Detailed Table of Contents for the C471 Lecture Notes

    2011-1-6 · For isatin, it is 91-56-5. Also produced by CAS are the CASREACT file of organic reaction data, the CHEMCATS file that links chemical substances with commercial suppliers, the CHEMLIST file of regulatory data, and a special variant of the CA File, CAPlus, that offers rapid coverage of the articles in the main journals of chemistry.

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  • Urea | NH2CONH2 - PubChem

    Urea is a nitrogenous compound containing a carbonyl group attached to two amine groups with osmotic diuretic activity. In vivo, urea is formed in the liver via the urea cycle from ammonia and is the final end product of protein metabolism. Administration of urea elevates blood plasma osmolality, resulting in enhanced flow of water from tissues, including the brain, cerebrospinal fluid and eye ...

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  • Synthesis of a new series of 3-functionalised-1-phenyl

    To the stirred solution of 3-(sulfamoyl)benzoic acid derivatives 3a–d (0.5 g, 2.5 mmol) in dry DMF (5 ml), EDCI (2.75 mmol), and HOBt (2.75 mmol) were added under inert conditions and the resultant solution stirred for 30 min at room temperature. This was followed by addition of propagyl amine (2.75 mmol) and the resultant solution was ...

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  • Zinc Dependent Histone Deacetylase Inhibitors in

    2021-2-3 · Title:Zinc Dependent Histone Deacetylase Inhibitors in Cancer Therapeutics: Recent Update VOLUME: 26 ISSUE: 40 Author(s):Faria Sultana, Kesari Lakshmi Manasa, Siddiq Pasha Shaik, Srinivasa Reddy Bonam and Ahmed Kamal* Affiliation:Medicinal Chemistry and Biotechnology Division, CSIR-Indian Institute of Chemical Technology (IICT), Hyderabad-500007, Medicinal Chemistry and …

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  • Carbonic anhydrase inhibitors and activators for novel ...

    2019-11-11 · Carbonic anhydrases (CAs, Enzyme Commission number 4.2.1.1) catalyze a simple but fundamental reaction, CO 2 hydration to yield bicarbonate and protons. CAs belonging to the α-, β-, γ-, δ- and ζ-families are found in many organisms all over the phylogenetic tree and their inhibition/activation have been studied in detail, leading to various therapeutic applications.

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  • Lactams | SCBT - Santa Cruz Biotechnology

    2827-56-7 sc-220458 : 5 g: 54.00 0 ... CAS: 86329-79-5, MF: C 20 H 18 N 6 O 7 S 4. 2 Na, MW: 628.63, Purity: ≥92% 86329-79-5 sc-278819 : 1.5 g: 400.00 ... 3158-91-6 sc-209132 : 1 g: 220.00 0 ...

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  • Functionalized Macrocycles in Supramolecular ...

    This macrocycle was used to catalyze the multicomponent reaction between isatin 2, dimedone 3 and toluidine 4 to yield the highly substituted pyrroloacridinone 5 (see Figure 1). 16 Little to no conversion was observed in absence of the catalyst, while presence of macrocyclic catalyst 1 (10 mol%) yielded the polycyclic product in up to 91 % ...

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  • Laboratory Chemicals | Manufacturers of Fine Chemicals ...

    2019-1-3 · 5 330. 60185 13019049 5 1350. 60190 38061010 5 490. 14725 13019017 18 670. 14728 29270090 18 310. 14728 29270090 18 950. 600703 18 380. 600703 18 1750. 600703 18 8400. 31810 38220090 12 320. 31815 29339900 18 400. 31815 29339900 18 1650. 31815 29339900 18 5350. 31840 18 2100. 31840 18 9000. 31841 18 470. 31842 18 420. 31845 18 560. 52780 ...

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  • Laboratory Chemicals | Manufacturers of Fine Chemicals ...

    2019-11-4 · 5 495. 11000 13012000 5 4250. 21000 13012000 5 800. 51010 29029090 18 520. 51010 29029090 18 1850. 11005 29241900 18 600. 11005 29241900 18 2280. 11005 29241900 18 8800. 11007 29241900 18 430. 11007 29241900 18 780. 11008 29241900 18 830. 11008 29241900 18 3050. 11010 29152990 18 510. 11010 29152990 18 890. 11030 38220090 12 180. 11040 29152100 ...

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